You can buy Orlistat (Xenical/Alli) as an over-the-counter alternative to Wegovy in the UK.
However, Orlistat is a very different type of weight-loss medication, and research suggests it’s not as effective as Wegovy in supporting weight loss.
Wegovy and Orlistat are weight-loss medications approved for use in the UK. However, they are different medications with distinct dosing schedules, costs, and mechanisms of action on the body.
Orlistat is a lipase inhibitor. Lipases are gut enzymes that break down fat from food, enabling the gut to transport fat into the body to be burnt for energy or stored in our fat cells for later use.
Orlistat blocks lipases, preventing some of the dietary fat from our meals from being digested. This leads to fewer calories being absorbed, which can support weight loss.
Orlistat is a prescription medication produced by two pharmaceutical companies in the UK:
Wegovy is a weight-loss jab manufactured by Novo Nordisk. It’s a weekly weight-loss injection with semaglutide as the active ingredient.
Semaglutide is a that helps reduce hunger and appetite, allowing you to eat fewer calories, lose weight, and manage your blood sugar levels.
Wegovy is approved in the UK for individuals living with obesity to help them eat fewer calories and lose weight.
The over-the-counter version of Orlistat will cost around £18 a month, so it’s a very affordable medication.
In comparison, buying Wegovy and the injectable pens required for four weeks from Second Nature will cost £229 a month, rising to £299.
Orlistat is an affordable medication that is generally well-tolerated. However, it’s less effective than Wegovy. Wegovy is twice as effective as Orlistat for weight loss after one year.
So, if you’re looking for the most affordable weight-loss pill you can purchase over the counter, then Orlistat could be an option.
However, if you have a higher budget and are looking for the most effective weight-loss injection in the UK, semaglutide is a better choice.
Semaglutide is designed as an additional tool for weight management and, in most cases, shouldn’t be considered a lifelong medication.
Instead, it should be used to help you kickstart your weight loss and healthy journey while you commit to living a healthier lifestyle.
Ideally, we’d be able to lose weight without medication and lifestyle changes would be enough to support weight loss in the long term.
We’d generally recommend trying Second Nature’s before considering a weight-loss jab.
Changing your habits is the most sustainable way to achieve long-term weight loss, and it’s also less expensive.
At Second Nature, we’ve been trusted by the NHS since 2017 to support people with type 2 diabetes and obesity to lose weight, manage their blood sugar levels, and lead healthier lifestyles for the long term.
In 2022, the NHS in the BMJ that compared the weight loss outcomes of five providers in the National Diabetes Prevention Programme.
Second Nature was more than twice as effective at supporting weight loss than the other four providers.
However, if you’ve decided to try semaglutide (when it’s available) but need support in making positive changes to your lifestyle, Second Nature could be an option for you. But it’s worth noting that we have strict eligibility criteria.
Second Nature has (among the few publicly-funded clinical trials for weight loss,) been an inspiration to other NHS providers when it comes to the dosing of weight-loss medications.We’ve put together a list of recommendations for weight-loss medications over the last few years.
Orlistat is used to treat obesity and help in weight loss. Orlistat is to be used along with a low-calorie diet and regular physical exercise. Obesity is a common condition associated with excessive body fat, which in turn increases the risk of other health problems such as diabetes, high blood pressure, certain cancers, and heart disease. Intake of more calories than you burn by exercise or daily activities results in obesity.
Orlistat contains Orlistat, which works in the small intestine and stomach and prevents the action of enzymes that break down fat, which is absorbed by the body. Orlistat decreases the absorption of fat from the food you eat. Thus, fat passes through the gut and is excreted in the faeces, which makes the body unable to use fat as a source of energy or convert it into fat tissue. Thereby, Orlistat helps in weight loss.
Take Orlistat as prescribed by your doctor. You are advised to take Orlistat for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience soft stools, sudden bowel motions, flatulence (gas) with or without oily spotting, oily or fatty stools, stomach pain, stool incontinence (involuntary leakage of stools), and runny or liquid stools. Most of these side effects of Orlistat do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.
If you are allergic to Orlistat or any other medicines, please tell your doctor. Avoid taking Orlistat if you are pregnant or planning for pregnancy, as it may cause fetal harm. It is not known whether Orlistat is excreted in human milk. Therefore, please consult a doctor if you are a breastfeeding woman. Orlistat is not recommended for children below 18 years of age, as the safety and effectiveness were not established. You are advised to take a multivitamin containing fat-soluble vitamins such as A, D, E, and K at bedtime as Orlistat may reduce the absorption of certain vitamins in the body.
Contains Orlistat - Tadalafil T1/2 6x as MedicationThe amount of fat in the body is reduced by Orlistat. Some fat cells are more sensitive to sunlight and need more sunlight to grow and multiply. Therefore, the number of cells in the body is reduced. The main active principle of Orlistat is breaking down fat by means of enzymes called lipases. These enzymes are responsible for breaking down the fat cells. Orlistat works by inhibiting the action of lipases, preventing the entry of dietary fat into the body. Thus, the absorption of fat is decreased. Orlistat has a very low molecular weight of T1/2 of 6,000. This suggests that Orlistat is not the right medication for your medical condition. If you have any further questions about Orlistat, please consult a doctor.
Orlistat is an active ingredient. Its mode of action is unknown. Orlistat is an antifungal medication, and there are no clinical studies to confirm the efficacy of Orlistat in the treatment of patients. Orlistat is an absorption inhibitor. The recommended dosage of Orlistat is 2 g/day. Some people experience soft stools, sudden bowel motions, flatulence (gas) with or without oily spotting, stomach pain, and stool incontinence (involuntary leakage of stools). Most of these side effects do not require medical attention and gradually resolve over time. However, please consult a doctor.
You are also prescribed with as Medication
Uses:Orlistat lowers the amount of fat absorbed by the body by enhancing caloric intake, thereby helping in the prevention of various health problems (diabetes, high blood pressure, high cholesterol, type 2 diabetes, runny or liquid stool).
How to use:You are also prescribed with Medication
Orlistat should be swallowed whole with water. The dosage of Orlistat is 2 g per day.
Precautions:Before taking Orlistat, tell your doctor about any age-related medical condition. Also, tell your doctor if you are allergic to Orlistat or any other medications.
Xenical 120mg Capsules,when used in conjunction with a reduced-calorie diet, can be used for obesity management, including weight loss and weight maintenance.Xenicalworks in your digestive system to block one-third of the fat in the food you eat from being digestedThe daily intake of fat, carbohydrate and protein should be distributed over three main meals.pills can also block the absorption of some vitamins. You may wish to take a multivitamin supplement along with making sure to keep a well-balanced diet, rich in fruit and vegetables.
The active substance isOrlistat. Each capsule contains120 mg of Orlistat
The other ingredients are microcrystalline cellulose (E460), sodium starch glycolate (type A), povidone (E1201), sodium laurilsulfate and talc. The capsule shell consists of gelatine, indigo carmine (E132), titanium dioxide (E171) and edible printing ink.
84 Capsules
We don’t recommend having a multivitamin on time or during your course of mult>The most common side effects are the following
Other side effects may include:
For medical advice about any adverse side effect, you should contact your doctor or pharmacistimmediatelyorby reason of change of life
Drinking alcohol or tobacco with Xenical 120mg can increase the risk of low blood sugar - especially when taken with other medications thatasley your blood sugar (e.g. phenytoin, carbamazepine, phenobarbital)
If you have diabetes, you may want to talk to your doctor before using Xenical 120mg. You should not take Xenical 120mg if you have one of these conditions.
For further information on Xenical, see the
For medical advice about any adverse side effects, you should not take Xenical 120mg if you have them.
For medical advice about any adverse side effects, you should not take Xenical 120mg if you have any of these conditions. You should talk to your doctor or pharmacist before taking Xenical if you have any of these conditions. You should not take Xenical if you are allergic to Orlistat or any of the other ingredients in Xenical.
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Alli is a top weight-loss brand in Turkey,...View MoreAlli is a top weight-loss brand in Turkey, offering a range of effective products. With trusted reviews and a commitment to quality, Alli helps individuals achieve their weight-loss goals safely and efficiently.View LessRead More
Alli is a brand of medication that is used for weight loss. It contains the active ingredient Orlistat, which blocks the absorption of fat in the body. Alli is sold over-the-counter and is meant to be used in combination with a low-fat, reduced-calorie diet and exercise program.
- Alli was launched in 2007 by GlaxoSmithKline.
- It was the first FDA-approved over-the-counter weight loss medication.
- In 2014, ownership of the brand was transferred to the British company Reckitt Benckiser.
- Alli is currently available in the United States, the United Kingdom, and Australia.
Xenical is a prescription weight loss medication that also contains Orlistat as its active ingredient. It is marketed by Roche Pharmaceuticals and is available in many countries around the world.
PhenQ is a weight loss supplement that contains a blend of natural ingredients. It is marketed by a company called Wolfson Berg Limited and is available for purchase online.
Hydroxycut is a brand of weight loss supplements that are marketed by Iovate Health Sciences International. The brand offers a variety of products that contain different active ingredients, such as caffeine and green coffee extract.
Alli Capsules are the brand's flagship product. Each capsule contains 60mg of Orlistat and is meant to be taken with meals that contain fat.
Alli is used for weight loss. It works by blocking the absorption of fat in the body.
Alli is meant to be taken with meals that contain fat. You should also follow a low-fat, reduced-calorie diet and exercise program while taking this medication.
Alli is generally considered safe when used as directed. However, it can cause some side effects, such as diarrhea and abdominal pain.
Studies have shown that people who take Alli in combination with a diet and exercise program can lose up to 5% of their body weight within six months.
No, Alli is not recommended for use during pregnancy or breastfeeding.
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